Revisiting Warfarin Dosing Using Machine Learning Techniques
نویسندگان
چکیده
منابع مشابه
Revisiting Warfarin Dosing Using Machine Learning Techniques
Determining the appropriate dosage of warfarin is an important yet challenging task. Several prediction models have been proposed to estimate a therapeutic dose for patients. The models are either clinical models which contain clinical and demographic variables or pharmacogenetic models which additionally contain the genetic variables. In this paper, a new methodology for warfarin dosing is pro...
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A high prevalence of genetic polymorphisms increases sensitivity to warfarin therapy. In this study, we investigated 47 patients with effective long-term therapy by warfarin well-controlled by monitoring of International Normalised Ratio (INR). All patients were tested for gene polymorphisms VKORC1, CYP2C9*C2, and CYP2C9*C3, which were used for a dose calculation employing a program www.Warfari...
متن کاملComparison of two different techniques of warfarin dosing determination - A chemometrics study
A high prevalence of genetic polymorphisms increases sensitivity to warfarin therapy. In this study, we investigated 47 patients with effective long-term therapy by warfarin well-controlled by monitoring of International Normalised Ratio (INR). All patients were tested for gene polymorphisms VKORC1, CYP2C9*C2, and CYP2C9*C3, which were used for a dose calculation employing a program www.Warfari...
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ژورنال
عنوان ژورنال: Computational and Mathematical Methods in Medicine
سال: 2015
ISSN: 1748-670X,1748-6718
DOI: 10.1155/2015/560108